Behaviour change after Polysulfated Glycosaminoglycan in horses

The FDA has received 26 reports of behaviour change in horses after Polysulfated Glycosaminoglycan. That is 5.0% of all reports for this medicine, compared with 3.7% across reports for all horse medicines.

26Reports
42%Marked serious
54%Recovered
0.0%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
7 41%
1–2 days
1 5.9%
3–7 days
2 12%
1–4 weeks
3 18%
Over a month
4 24%

How the animals did

Recovered
14 54%
Still unwell when reported
1 3.8%
Not known
11 42%

Problems reported at the same time

8 31%
Muscle stiffness
2 7.7%
Reluctant to move
2 7.7%
Pawing
2 7.7%

Age of the animals

Under 1 year
0
1–3 years
3
4–7 years
2
8–11 years
3
12+ years
16

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause behaviour change in horses?
26 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in horses · Medicines most reported with behaviour change