Behaviour change after Pergolide in horses

121 reports to the FDA describe behaviour change in horses given Pergolide. That is 9.8% of all reports for this medicine, compared with 3.7% across reports for all horse medicines, so it is reported unusually often with this medicine.

121Reports
19%Marked serious
36%Recovered
4.1%Died or euthanised
10 daysTypical onset
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How soon it started

Same day
17 19%
1–2 days
9 10%
3–7 days
17 19%
1–4 weeks
21 23%
Over a month
26 29%

How the animals did

Recovered
42 35%
Recovered with lasting effects
1 0.8%
Still unwell when reported
12 9.9%
Died
2 1.7%
Euthanised
3 2.5%
Not known
61 50%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
0
4–7 years
2
8–11 years
4
12+ years
91

About this medicine

Type: medicine.

Questions owners ask

Can Pergolide cause behaviour change in horses?
121 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 10 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

All reported side effects of Pergolide in horses · Medicines most reported with behaviour change