Tremors after Trilostane (Vetoryl) in dogs

751 reports to the FDA describe tremors in dogs given Trilostane. That is 6.3% of all reports for this medicine, compared with 3.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

751Reports

54%Marked serious

18%Recovered

15%Died or euthanised

29 daysTypical onset

How soon it started

Same day

55 9.2%

1–2 days

54 9.0%

3–7 days

61 10%

1–4 weeks

141 24%

Over a month

287 48%

How the animals did

Recovered

131 17%

Recovered with lasting effects

3 0.4%

Still unwell when reported

95 13%

Died

33 4.4%

Euthanised

83 11%

Not known

406 54%

Problems reported at the same time

303 40%

229 30%

198 26%

168 22%

137 18%

125 17%

122 16%

119 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

345

12+ years

330

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause tremors in dogs?: 751 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 29 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Tremors with similar medicines

Tremors after Insulin 191 reports · 2.6% of its reports
Tremors after Phenylpropanolamine (Proin) 166 reports · 4.0% of its reports
Tremors after Levothyroxine 132 reports · 4.4% of its reports

All reported side effects of Trilostane in dogs · Medicines most reported with tremors