Skin scab after Trilostane (Vetoryl) in dogs

The FDA has received 28 reports of skin scab in dogs after Trilostane. That is 0.2% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.

28Reports

75%Marked serious

7.1%Recovered

7.1%Died or euthanised

45 daysTypical onset

How soon it started

Same day

0 0.0%

1–2 days

1 4.2%

3–7 days

2 8.3%

1–4 weeks

8 33%

Over a month

13 54%

How the animals did

Recovered

2 7.1%

Still unwell when reported

7 25%

Euthanised

2 7.1%

Not known

17 61%

Problems reported at the same time

Hair loss

13 46%

Skin rash or irritation

10 36%

8 29%

8 29%

6 21%

5 18%

5 18%

Skin slough

5 18%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause skin scab in dogs?: 28 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 45 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Skin scab with similar medicines

Skin scab after Levothyroxine 23 reports · 0.8% of its reports

All reported side effects of Trilostane in dogs · Medicines most reported with skin scab