Drug dose administration interval too short after Trilostane (Vetoryl) in dogs

77 reports to the FDA describe drug dose administration interval too short in dogs given Trilostane. That is 0.6% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

77Reports
42%Marked serious
17%Recovered
6.5%Died or euthanised
45 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
1 1.8%
1–2 days
7 13%
3–7 days
4 7.1%
1–4 weeks
12 21%
Over a month
32 57%

How the animals did

Recovered
13 17%
Still unwell when reported
8 10%
Died
2 2.6%
Euthanised
3 3.9%
Not known
51 66%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
0
4–7 years
6
8–11 years
36
12+ years
35

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause drug dose administration interval too short in dogs?
77 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 45 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Drug dose administration interval too short with similar medicines

All reported side effects of Trilostane in dogs · Medicines most reported with drug dose administration interval too short