Digestive tract disorder after Trilostane (Vetoryl) in dogs

The FDA has received 36 reports of digestive tract disorder in dogs after Trilostane. That is 0.3% of all reports for this medicine, compared with 2.0% across reports for all dog medicines, so it is reported less often than average with this medicine.

36Reports

61%Marked serious

22%Recovered

5.6%Died or euthanised

60 daysTypical onset

How soon it started

Same day

1 4.0%

1–2 days

0 0.0%

3–7 days

3 12%

1–4 weeks

5 20%

Over a month

16 64%

How the animals did

Recovered

6 17%

Recovered with lasting effects

2 5.6%

Still unwell when reported

7 19%

Died

2 5.6%

Not known

19 53%

Problems reported at the same time

14 39%

12 33%

12 33%

8 22%

8 22%

7 19%

Didn't work as expected

6 17%

Vomiting

6 17%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause digestive tract disorder in dogs?: 36 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 60 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Digestive tract disorder with similar medicines

Digestive tract disorder after Insulin 26 reports · 0.4% of its reports

All reported side effects of Trilostane in dogs · Medicines most reported with digestive tract disorder