Cough after Trilostane (Vetoryl) in dogs

The FDA has received 163 reports of cough in dogs after Trilostane. That is 1.4% of all reports for this medicine, compared with 0.8% across reports for all dog medicines, so it is reported unusually often with this medicine.

163Reports
65%Marked serious
8.0%Recovered
12%Died or euthanised
53 daysTypical onset
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How soon it started

Same day
6 5.7%
1–2 days
5 4.7%
3–7 days
12 11%
1–4 weeks
21 20%
Over a month
62 58%

How the animals did

Recovered
12 7.4%
Recovered with lasting effects
1 0.6%
Still unwell when reported
31 19%
Died
7 4.3%
Euthanised
12 7.4%
Not known
100 61%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
0
4–7 years
3
8–11 years
59
12+ years
95

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause cough in dogs?
163 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 53 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Cough with similar medicines

All reported side effects of Trilostane in dogs · Medicines most reported with cough