Lethargy after Tacrolimus in dogs

50 reports to the FDA describe lethargy in dogs given Tacrolimus. That is 17% of all reports for this medicine, compared with 11% across reports for all dog medicines.

50Reports
64%Marked serious
28%Recovered
26%Died or euthanised
68 daysTypical onset
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How soon it started

Same day
2 7.1%
1–2 days
5 18%
3–7 days
4 14%
1–4 weeks
1 3.6%
Over a month
16 57%

How the animals did

Recovered
10 20%
Recovered with lasting effects
4 8.0%
Still unwell when reported
10 20%
Died
4 8.0%
Euthanised
9 18%
Not known
13 26%

Problems reported at the same time

18 36%
15 30%
13 26%
Corneal disorder
9 18%
Corneal ulcer
8 16%

Age of the animals

Under 1 year
0
1–3 years
3
4–7 years
12
8–11 years
18
12+ years
17

About this medicine

Type: medicine.

Questions owners ask

Can Tacrolimus cause lethargy in dogs?
50 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 68 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Tacrolimus in dogs · Medicines most reported with lethargy