Tacrolimus side effects in dogs

297 reports sent to the FDA between 2011 and 2026 involve Tacrolimus in dogs. The most reported problems were vomiting, lethargy, loss of appetite. 44% were marked serious, and where it was recorded, signs eased after stopping the medicine in 100% of cases.

297Reports
44%Marked serious
3.4%Only medicine involved
32%Recovered
10%Died or euthanised
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About this medicine

Type: medicine.

Most reported side effects

72 24%
50 17%
33 11%
22 7.4%
Corneal ulcer
19 6.4%
Breathing problems
19 6.4%
Excessive urination
17 5.7%
Blood problems
17 5.7%
Hair loss
16 5.4%
Skin rash or irritation
15 5.1%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't stop worms
4 1.3%
Didn't prevent heartworm
4 1.3%
Didn't stop fleas
2 0.7%

How soon problems started

Same day
27 15%
1–2 days
14 7.7%
3–7 days
21 12%
1–4 weeks
16 8.8%
Over a month
104 57%

Time from the first dose to the first sign, where both dates were reported (182 reports).

How the animals did

Recovered
81 27%
Recovered with lasting effects
13 4.4%
Still unwell when reported
93 31%
Died
10 3.4%
Euthanised
21 7.1%
Not known
79 27%

Breeds named most often

Popular breeds appear more often because there are more of them.

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