Loss of appetite after Tacrolimus in dogs

The FDA has received 47 reports of loss of appetite in dogs after Tacrolimus. That is 16% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

47Reports
74%Marked serious
17%Recovered
32%Died or euthanised
36 daysTypical onset
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How soon it started

Same day
4 13%
1–2 days
6 20%
3–7 days
3 10%
1–4 weeks
2 6.7%
Over a month
15 50%

How the animals did

Recovered
5 11%
Recovered with lasting effects
3 6.4%
Still unwell when reported
13 28%
Died
4 8.5%
Euthanised
11 23%
Not known
11 23%

Problems reported at the same time

28 60%
21 45%
15 32%
11 23%
Corneal ulcer
10 21%

Age of the animals

Under 1 year
0
1–3 years
0
4–7 years
13
8–11 years
17
12+ years
17

About this medicine

Type: medicine.

Questions owners ask

Can Tacrolimus cause loss of appetite in dogs?
47 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 36 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

All reported side effects of Tacrolimus in dogs · Medicines most reported with loss of appetite