Underdose after Spinosad (Comfortis) in dogs
365 reports to the FDA describe underdose in dogs given Spinosad. That is 0.6% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported less often than average with this medicine.
365Reports
7.9%Marked serious
26%Recovered
0.5%Died or euthanised
13 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Spinosad kills fleas; monthly chewable.
Products with this ingredient include Comfortis. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Spinosad cause underdose in dogs?
- 365 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 13 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Underdose with similar medicines
- Underdose after Lufenuron + Milbemycin Oxime (Sentinel) 332 reports · 1.3% of its reports
- Underdose after Imidacloprid + Moxidectin (Advantage Multi) 144 reports · 1.1% of its reports
- Underdose after Nitenpyram (Capstar) 139 reports · 1.3% of its reports
- Underdose after Lufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum) 132 reports · 1.3% of its reports
- Underdose after Fipronil + S-methoprene (Frontline Plus) 31 reports · 1.0% of its reports
- Underdose after Imidacloprid 48 reports · 2.5% of its reports
All reported side effects of Spinosad in dogs · Medicines most reported with underdose