Fever after Selegiline (Anipryl) in dogs

The FDA has received 36 reports of fever in dogs after Selegiline. That is 0.9% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported less often than average with this medicine.

36Reports

5.6%Marked serious

0.0%Recovered

36%Died or euthanised

–Typical onset

How the animals did

Still unwell when reported

2 5.6%

Died

12 33%

Euthanised

1 2.8%

Not known

21 58%

Problems reported at the same time

15 42%

14 39%

13 36%

11 31%

10 28%

8 22%

6 17%

Restlessness or agitation

5 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Selegiline treats canine cognitive dysfunction.

Products with this ingredient include Anipryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Selegiline cause fever in dogs?: 36 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Fever with similar medicines

Fever after Gabapentin 282 reports · 3.1% of its reports
Fever after Trazodone 76 reports · 3.0% of its reports
Fever after Clomipramine (Clomicalm) 25 reports · 1.7% of its reports

All reported side effects of Selegiline in dogs · Medicines most reported with fever