Fever after Trazodone in dogs

The FDA has received 76 reports of fever in dogs after Trazodone. That is 3.0% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

76Reports

86%Marked serious

11%Recovered

28%Died or euthanised

5 daysTypical onset

How soon it started

Same day

13 19%

1–2 days

17 25%

3–7 days

7 10%

1–4 weeks

8 12%

Over a month

23 34%

How the animals did

Recovered

8 11%

Still unwell when reported

36 47%

Died

4 5.3%

Euthanised

17 22%

Not known

11 14%

Problems reported at the same time

40 53%

35 46%

28 37%

22 29%

21 28%

18 24%

18 24%

18 24%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trazodone reduces anxiety and stress.

Questions owners ask

Can Trazodone cause fever in dogs?: 76 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Fever with similar medicines

Fever after Gabapentin 282 reports · 3.1% of its reports
Fever after Selegiline (Anipryl) 36 reports · 0.9% of its reports
Fever after Clomipramine (Clomicalm) 25 reports · 1.7% of its reports

All reported side effects of Trazodone in dogs · Medicines most reported with fever