Vocalising after Sarolaner (Simparica) in dogs

174 reports to the FDA describe vocalising in dogs given Sarolaner. That is 1.0% of all reports for this medicine, compared with 1.2% across reports for all dog medicines.

174Reports
51%Marked serious
17%Recovered
13%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
64 41%
1–2 days
48 31%
3–7 days
12 7.6%
1–4 weeks
18 11%
Over a month
15 9.6%

How the animals did

Recovered
29 17%
Still unwell when reported
74 43%
Died
15 8.6%
Euthanised
7 4.0%
Not known
49 28%

Problems reported at the same time

Age of the animals

Under 1 year
16
1–3 years
28
4–7 years
54
8–11 years
46
12+ years
28

About this medicine

Sarolaner kills fleas, ticks and some mites; monthly.

Products with this ingredient include Simparica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Sarolaner cause vocalising in dogs?
174 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vocalising with similar medicines

All reported side effects of Sarolaner in dogs · Medicines most reported with vocalising