Loss of appetite after S-adenosylmethionine Silybin in dogs

The FDA has received 42 reports of loss of appetite in dogs after S-adenosylmethionine Silybin. That is 17% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

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How soon it started

How the animals did

Problems reported at the same time

Age of the animals

About this medicine

Type: medicine.

Questions owners ask

Can S-adenosylmethionine Silybin cause loss of appetite in dogs?

42 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.

How soon after a dose was it reported?

In half of the reports with dates, it started within 46 days of the first dose.

What should I do?

Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

• Loss of appetite after Melarsomine (Immiticide) 1,950 reports · 8.6% of its reports
• Loss of appetite after Polysulfated Glycosaminoglycan 1,132 reports · 21% of its reports
• Loss of appetite after Diphenhydramine 901 reports · 19% of its reports
• Loss of appetite after Butorphanol 706 reports · 16% of its reports
• Loss of appetite after Cefpodoxime 709 reports · 17% of its reports
• Loss of appetite after Tramadol 1,040 reports · 28% of its reports
• Loss of appetite after Florfenicol + Mometasone + Terbinafine 475 reports · 13% of its reports
• Loss of appetite after Desoxycorticosterone Pivalate 487 reports · 15% of its reports
• Loss of appetite after Propofol 372 reports · 12% of its reports
• Loss of appetite after Dirlotapide 530 reports · 19% of its reports

All reported side effects of S-adenosylmethionine Silybin in dogs · Medicines most reported with loss of appetite