Decreased red blood cell count after Pyrantel + Sarolaner (Simparica Trio) in dogs
28 reports to the FDA describe decreased red blood cell count in dogs given Pyrantel + Sarolaner. That is 0.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported less often than average with this medicine.
28Reports
93%Marked serious
11%Recovered
29%Died or euthanised
22 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Pyrantel treats roundworms and hookworms. Sarolaner kills fleas, ticks and some mites; monthly.
Products with this combination include Simparica Trio (which also contains moxidectin). The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Pyrantel + Sarolaner cause decreased red blood cell count in dogs?
- 28 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 22 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Decreased red blood cell count with similar medicines
- Decreased red blood cell count after Fenbendazole 28 reports · 0.5% of its reports
All reported side effects of Pyrantel + Sarolaner in dogs · Medicines most reported with decreased red blood cell count