Itching after Praziquantel + Pyrantel in dogs

The FDA has received 81 reports of itching in dogs after Praziquantel + Pyrantel. That is 2.2% of all reports for this medicine, compared with 4.3% across reports for all dog medicines, so it is reported less often than average with this medicine.

81Reports
38%Marked serious
30%Recovered
3.7%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
40 63%
1–2 days
9 14%
3–7 days
5 7.9%
1–4 weeks
3 4.8%
Over a month
6 9.5%

How the animals did

Recovered
23 28%
Recovered with lasting effects
1 1.2%
Still unwell when reported
10 12%
Died
3 3.7%
Not known
44 54%

Problems reported at the same time

Age of the animals

Under 1 year
26
1–3 years
26
4–7 years
17
8–11 years
9
12+ years
2

About this medicine

Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Praziquantel + Pyrantel cause itching in dogs?
81 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Itching with similar medicines

All reported side effects of Praziquantel + Pyrantel in dogs · Medicines most reported with itching