Blood in vomit after Praziquantel + Pyrantel in dogs

38 reports to the FDA describe blood in vomit in dogs given Praziquantel + Pyrantel. That is 1.0% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

38Reports

68%Marked serious

18%Recovered

32%Died or euthanised

1 daysTypical onset

How soon it started

Same day

12 41%

1–2 days

16 55%

3–7 days

1 3.4%

1–4 weeks

0 0.0%

Over a month

0 0.0%

How the animals did

Recovered

7 18%

Died

12 32%

Not known

19 50%

Problems reported at the same time

20 53%

12 32%

12 32%

11 29%

10 26%

4 11%

Unable to walk

3 7.9%

Drug administration error

2 5.3%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Praziquantel + Pyrantel cause blood in vomit in dogs?: 38 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood in vomit with similar medicines

Blood in vomit after Pyrantel + Sarolaner (Simparica Trio) 114 reports · 0.2% of its reports
Blood in vomit after Febantel + Praziquantel + Pyrantel (Drontal Plus) 20 reports · 0.3% of its reports
Blood in vomit after Fenbendazole 44 reports · 0.7% of its reports
Blood in vomit after Pyrantel 47 reports · 1.0% of its reports

All reported side effects of Praziquantel + Pyrantel in dogs · Medicines most reported with blood in vomit