Blood in stool after Praziquantel + Pyrantel in dogs

31 reports to the FDA describe blood in stool in dogs given Praziquantel + Pyrantel. That is 0.8% of all reports for this medicine, compared with 0.6% across reports for all dog medicines.

31Reports

32%Marked serious

16%Recovered

6.5%Died or euthanised

2 daysTypical onset

How soon it started

Same day

2 18%

1–2 days

7 64%

3–7 days

2 18%

1–4 weeks

0 0.0%

Over a month

0 0.0%

How the animals did

Recovered

5 16%

Died

2 6.5%

Not known

24 77%

Problems reported at the same time

14 45%

12 39%

8 26%

7 23%

3 9.7%

2 6.5%

2 6.5%

Not himself/herself

2 6.5%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Praziquantel + Pyrantel cause blood in stool in dogs?: 31 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood in stool with similar medicines

Blood in stool after Pyrantel + Sarolaner (Simparica Trio) 43 reports · 0.1% of its reports
Blood in stool after Febantel + Praziquantel + Pyrantel (Drontal Plus) 27 reports · 0.4% of its reports
Blood in stool after Fenbendazole 60 reports · 1.0% of its reports
Blood in stool after Pyrantel 77 reports · 1.6% of its reports

All reported side effects of Praziquantel + Pyrantel in dogs · Medicines most reported with blood in stool