Blood in faeces after Praziquantel + Pyrantel in dogs

The FDA has received 53 reports of blood in faeces in dogs after Praziquantel + Pyrantel. That is 1.4% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

53Reports

47%Marked serious

26%Recovered

9.4%Died or euthanised

1 daysTypical onset

How soon it started

Same day

16 33%

1–2 days

25 51%

3–7 days

3 6.1%

1–4 weeks

0 0.0%

Over a month

5 10%

How the animals did

Recovered

14 26%

Still unwell when reported

3 5.7%

Died

3 5.7%

Euthanised

2 3.8%

Not known

31 58%

Problems reported at the same time

18 34%

18 34%

18 34%

13 25%

8 15%

5 9.4%

4 7.5%

4 7.5%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Praziquantel + Pyrantel cause blood in faeces in dogs?: 53 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood in faeces with similar medicines

Blood in faeces after Pyrantel + Sarolaner (Simparica Trio) 99 reports · 0.2% of its reports
Blood in faeces after Febantel + Praziquantel + Pyrantel (Drontal Plus) 34 reports · 0.5% of its reports
Blood in faeces after Fenbendazole 43 reports · 0.7% of its reports
Blood in faeces after Pyrantel 42 reports · 0.9% of its reports

All reported side effects of Praziquantel + Pyrantel in dogs · Medicines most reported with blood in faeces