Low platelet count after Ondansetron in dogs

The FDA has received 28 reports of low platelet count in dogs after Ondansetron. That is 4.2% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

28Reports
100%Marked serious
3.6%Recovered
57%Died or euthanised
14 daysTypical onset
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How soon it started

Same day
6 23%
1–2 days
1 3.8%
3–7 days
5 19%
1–4 weeks
4 15%
Over a month
10 38%

How the animals did

Recovered
1 3.6%
Still unwell when reported
7 25%
Died
4 14%
Euthanised
12 43%
Not known
4 14%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
4
4–7 years
10
8–11 years
11
12+ years
1

About this medicine

Type: medicine.

Questions owners ask

Can Ondansetron cause low platelet count in dogs?
28 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 14 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Low platelet count with similar medicines

All reported side effects of Ondansetron in dogs · Medicines most reported with low platelet count