Low platelet count after Melarsomine (Immiticide) in dogs

58 reports to the FDA describe low platelet count in dogs given Melarsomine. That is 0.3% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.

58Reports

72%Marked serious

3.4%Recovered

10%Died or euthanised

17 daysTypical onset

How soon it started

Same day

6 11%

1–2 days

3 5.6%

3–7 days

7 13%

1–4 weeks

16 30%

Over a month

22 41%

How the animals did

Recovered

2 3.4%

Still unwell when reported

28 48%

Died

2 3.4%

Euthanised

4 6.9%

Not known

22 38%

Problems reported at the same time

33 57%

28 48%

21 36%

20 34%

14 24%

14 24%

13 22%

13 22%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause low platelet count in dogs?: 58 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 17 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Low platelet count with similar medicines

Low platelet count after Polysulfated Glycosaminoglycan 70 reports · 1.3% of its reports
Low platelet count after Diphenhydramine 50 reports · 1.1% of its reports
Low platelet count after Butorphanol 28 reports · 0.6% of its reports
Low platelet count after Cefpodoxime 43 reports · 1.1% of its reports
Low platelet count after Tramadol 45 reports · 1.2% of its reports
Low platelet count after Propofol 24 reports · 0.8% of its reports
Low platelet count after Isoflurane 28 reports · 1.0% of its reports
Low platelet count after Cephalexin 21 reports · 0.8% of its reports
Low platelet count after Famotidine 54 reports · 2.0% of its reports
Low platelet count after Chondroitin + Glucosamine 23 reports · 0.9% of its reports

All reported side effects of Melarsomine in dogs · Medicines most reported with low platelet count