Hypoalbuminaemia after Ondansetron in dogs

The FDA has received 55 reports of hypoalbuminaemia in dogs after Ondansetron. That is 8.3% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

55Reports
84%Marked serious
11%Recovered
45%Died or euthanised
5 daysTypical onset
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How soon it started

Same day
15 33%
1–2 days
6 13%
3–7 days
4 8.7%
1–4 weeks
3 6.5%
Over a month
18 39%

How the animals did

Recovered
6 11%
Still unwell when reported
20 36%
Died
7 13%
Euthanised
18 33%
Not known
4 7.3%

Problems reported at the same time

Age of the animals

Under 1 year
5
1–3 years
10
4–7 years
18
8–11 years
14
12+ years
8

About this medicine

Type: medicine.

Questions owners ask

Can Ondansetron cause hypoalbuminaemia in dogs?
55 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 5 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypoalbuminaemia with similar medicines

All reported side effects of Ondansetron in dogs · Medicines most reported with hypoalbuminaemia