Hypoalbuminaemia after Tramadol in dogs

The FDA has received 106 reports of hypoalbuminaemia in dogs after Tramadol. That is 2.8% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

106Reports
82%Marked serious
12%Recovered
32%Died or euthanised
9 daysTypical onset
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How soon it started

Same day
8 10%
1–2 days
11 14%
3–7 days
16 21%
1–4 weeks
15 19%
Over a month
27 35%

How the animals did

Recovered
13 12%
Still unwell when reported
48 45%
Died
12 11%
Euthanised
22 21%
Not known
11 10%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
13
4–7 years
35
8–11 years
39
12+ years
18

About this medicine

Type: medicine.

Questions owners ask

Can Tramadol cause hypoalbuminaemia in dogs?
106 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 9 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypoalbuminaemia with similar medicines

All reported side effects of Tramadol in dogs · Medicines most reported with hypoalbuminaemia