Fever after Ondansetron in dogs

The FDA has received 66 reports of fever in dogs after Ondansetron. That is 9.9% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

66Reports
89%Marked serious
12%Recovered
48%Died or euthanised
5 daysTypical onset
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How soon it started

Same day
15 25%
1–2 days
10 17%
3–7 days
8 13%
1–4 weeks
7 12%
Over a month
20 33%

How the animals did

Recovered
8 12%
Still unwell when reported
23 35%
Died
10 15%
Euthanised
22 33%
Not known
3 4.5%

Problems reported at the same time

Age of the animals

Under 1 year
13
1–3 years
12
4–7 years
18
8–11 years
17
12+ years
6

About this medicine

Type: medicine.

Questions owners ask

Can Ondansetron cause fever in dogs?
66 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 5 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Fever with similar medicines

All reported side effects of Ondansetron in dogs · Medicines most reported with fever