Vocalising after Oclacitinib (Apoquel) in dogs

The FDA has received 291 reports of vocalising in dogs after Oclacitinib. That is 1.0% of all reports for this medicine, compared with 1.2% across reports for all dog medicines.

291Reports
42%Marked serious
21%Recovered
15%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
71 31%
1–2 days
21 9.3%
3–7 days
22 9.7%
1–4 weeks
36 16%
Over a month
76 34%

How the animals did

Recovered
60 21%
Recovered with lasting effects
1 0.3%
Still unwell when reported
128 44%
Died
18 6.2%
Euthanised
26 8.9%
Not known
58 20%

Problems reported at the same time

Age of the animals

Under 1 year
3
1–3 years
48
4–7 years
86
8–11 years
97
12+ years
49

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause vocalising in dogs?
291 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vocalising with similar medicines

All reported side effects of Oclacitinib in dogs · Medicines most reported with vocalising