Vocalising after Cyclosporine (Atopica) in dogs

The FDA has received 224 reports of vocalising in dogs after Cyclosporine. That is 1.5% of all reports for this medicine, compared with 1.2% across reports for all dog medicines.

224Reports

37%Marked serious

23%Recovered

12%Died or euthanised

5 daysTypical onset

How soon it started

Same day

24 30%

1–2 days

12 15%

3–7 days

4 5.1%

1–4 weeks

18 23%

Over a month

21 27%

How the animals did

Recovered

48 21%

Recovered with lasting effects

3 1.3%

Still unwell when reported

28 13%

Died

16 7.1%

Euthanised

10 4.5%

Not known

119 53%

Problems reported at the same time

Vomiting

70 31%

Lethargy

63 28%

Restlessness or agitation

57 25%

55 25%

46 21%

44 20%

34 15%

30 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause vocalising in dogs?: 224 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vocalising with similar medicines

Vocalising after Oclacitinib (Apoquel) 291 reports · 1.0% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with vocalising