Pain after Cyclosporine (Atopica) in dogs

The FDA has received 151 reports of pain in dogs after Cyclosporine. That is 1.0% of all reports for this medicine, compared with 0.7% across reports for all dog medicines.

151Reports

40%Marked serious

13%Recovered

19%Died or euthanised

7 daysTypical onset

How soon it started

Same day

15 33%

1–2 days

3 6.7%

3–7 days

5 11%

1–4 weeks

13 29%

Over a month

9 20%

How the animals did

Recovered

19 13%

Recovered with lasting effects

1 0.7%

Still unwell when reported

17 11%

Died

16 11%

Euthanised

13 8.6%

Not known

85 56%

Problems reported at the same time

53 35%

49 32%

49 32%

34 23%

30 20%

29 19%

24 16%

24 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause pain in dogs?: 151 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pain with similar medicines

Pain after Oclacitinib (Apoquel) 205 reports · 0.7% of its reports
Pain after Ilunocitinib (Zenrelia) 36 reports · 1.6% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with pain