Tense abdomen after Oclacitinib (Apoquel) in dogs

66 reports to the FDA describe tense abdomen in dogs given Oclacitinib. That is 0.2% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

66Reports

62%Marked serious

11%Recovered

27%Died or euthanised

18 daysTypical onset

How soon it started

Same day

7 14%

1–2 days

7 14%

3–7 days

3 6.1%

1–4 weeks

10 20%

Over a month

22 45%

How the animals did

Recovered

7 11%

Still unwell when reported

31 47%

Died

1 1.5%

Euthanised

17 26%

Not known

10 15%

Problems reported at the same time

38 58%

31 47%

31 47%

22 33%

19 29%

18 27%

13 20%

11 17%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause tense abdomen in dogs?: 66 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 18 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Tense abdomen with similar medicines

Tense abdomen after Cyclosporine (Atopica) 21 reports · 0.1% of its reports

All reported side effects of Oclacitinib in dogs · Medicines most reported with tense abdomen