Haematuria after Oclacitinib (Apoquel) in dogs

211 reports to the FDA describe haematuria in dogs given Oclacitinib. That is 0.7% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

211Reports

42%Marked serious

12%Recovered

9.0%Died or euthanised

61 daysTypical onset

How soon it started

Same day

13 9.4%

1–2 days

11 8.0%

3–7 days

10 7.2%

1–4 weeks

17 12%

Over a month

87 63%

How the animals did

Recovered

25 12%

Still unwell when reported

138 65%

Died

7 3.3%

Euthanised

12 5.7%

Not known

29 14%

Problems reported at the same time

Proteinuria

62 29%

Urinary tract infection

60 28%

50 24%

44 21%

40 19%

34 16%

32 15%

Didn't work as expected

30 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause haematuria in dogs?: 211 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 61 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Haematuria with similar medicines

Haematuria after Cyclosporine (Atopica) 159 reports · 1.0% of its reports
Haematuria after Ilunocitinib (Zenrelia) 34 reports · 1.5% of its reports

All reported side effects of Oclacitinib in dogs · Medicines most reported with haematuria