Distension of abdomen after Oclacitinib (Apoquel) in dogs

100 reports to the FDA describe distension of abdomen in dogs given Oclacitinib. That is 0.3% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.

100Reports

73%Marked serious

4.0%Recovered

33%Died or euthanised

65 daysTypical onset

How soon it started

Same day

6 9.4%

1–2 days

3 4.7%

3–7 days

6 9.4%

1–4 weeks

10 16%

Over a month

39 61%

How the animals did

Recovered

4 4.0%

Still unwell when reported

56 56%

Died

9 9.0%

Euthanised

24 24%

Not known

7 7.0%

Problems reported at the same time

37 37%

36 36%

33 33%

31 31%

25 25%

22 22%

Abnormal radiograph finding

21 21%

Hypoalbuminaemia

20 20%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause distension of abdomen in dogs?: 100 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 65 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Distension of abdomen with similar medicines

Distension of abdomen after Cyclosporine (Atopica) 60 reports · 0.4% of its reports

All reported side effects of Oclacitinib in dogs · Medicines most reported with distension of abdomen