Blood in urine after Oclacitinib (Apoquel) in dogs

165 reports to the FDA describe blood in urine in dogs given Oclacitinib. That is 0.6% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

165Reports

35%Marked serious

7.3%Recovered

3.6%Died or euthanised

35 daysTypical onset

How soon it started

Same day

12 9.8%

1–2 days

11 8.9%

3–7 days

20 16%

1–4 weeks

17 14%

Over a month

63 51%

How the animals did

Recovered

12 7.3%

Still unwell when reported

131 79%

Died

1 0.6%

Euthanised

5 3.0%

Not known

16 9.7%

Problems reported at the same time

Urinary tract infection

41 25%

34 21%

32 19%

27 16%

25 15%

23 14%

Decreased urine concentration

23 14%

Vomiting

22 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause blood in urine in dogs?: 165 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 35 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood in urine with similar medicines

Blood in urine after Cyclosporine (Atopica) 28 reports · 0.2% of its reports
Blood in urine after Ilunocitinib (Zenrelia) 26 reports · 1.2% of its reports

All reported side effects of Oclacitinib in dogs · Medicines most reported with blood in urine