Abdominal pain after Oclacitinib (Apoquel) in dogs

116 reports to the FDA describe abdominal pain in dogs given Oclacitinib. That is 0.4% of all reports for this medicine, compared with 0.4% across reports for all dog medicines.

116Reports

59%Marked serious

14%Recovered

25%Died or euthanised

22 daysTypical onset

How soon it started

Same day

7 8.4%

1–2 days

14 17%

3–7 days

12 14%

1–4 weeks

14 17%

Over a month

36 43%

How the animals did

Recovered

16 14%

Still unwell when reported

62 53%

Died

11 9.5%

Euthanised

18 16%

Not known

9 7.8%

Problems reported at the same time

61 53%

57 49%

51 44%

39 34%

36 31%

28 24%

Abnormal radiograph finding

24 21%

Fever

23 20%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause abdominal pain in dogs?: 116 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 22 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abdominal pain with similar medicines

Abdominal pain after Cyclosporine (Atopica) 151 reports · 1.0% of its reports

All reported side effects of Oclacitinib in dogs · Medicines most reported with abdominal pain