Unresponsive after Melarsomine (Immiticide) in dogs

The FDA has received 123 reports of unresponsive in dogs after Melarsomine. That is 0.5% of all reports for this medicine, compared with 0.4% across reports for all dog medicines.

123Reports
67%Marked serious
20%Recovered
24%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
20 24%
1–2 days
6 7.3%
3–7 days
17 21%
1–4 weeks
14 17%
Over a month
25 30%

How the animals did

Recovered
24 20%
Still unwell when reported
18 15%
Died
18 15%
Euthanised
11 8.9%
Not known
52 42%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
55
4–7 years
50
8–11 years
13
12+ years
3

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause unresponsive in dogs?
123 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Unresponsive with similar medicines

All reported side effects of Melarsomine in dogs · Medicines most reported with unresponsive