Unresponsive after Tramadol in dogs

The FDA has received 39 reports of unresponsive in dogs after Tramadol. That is 1.0% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

39Reports
79%Marked serious
18%Recovered
49%Died or euthanised
16 daysTypical onset
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How soon it started

Same day
7 23%
1–2 days
4 13%
3–7 days
2 6.5%
1–4 weeks
8 26%
Over a month
10 32%

How the animals did

Recovered
5 13%
Recovered with lasting effects
2 5.1%
Still unwell when reported
10 26%
Died
11 28%
Euthanised
8 21%
Not known
3 7.7%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
1
4–7 years
7
8–11 years
16
12+ years
14

About this medicine

Type: medicine.

Questions owners ask

Can Tramadol cause unresponsive in dogs?
39 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 16 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Unresponsive with similar medicines

All reported side effects of Tramadol in dogs · Medicines most reported with unresponsive