Abnormal cytology after Melarsomine (Immiticide) in dogs

126 reports to the FDA describe abnormal cytology in dogs given Melarsomine. That is 0.6% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

126Reports

33%Marked serious

1.6%Recovered

1.6%Died or euthanised

28 daysTypical onset

How soon it started

Same day

6 5.0%

1–2 days

5 4.1%

3–7 days

8 6.6%

1–4 weeks

51 42%

Over a month

51 42%

How the animals did

Recovered

2 1.6%

Still unwell when reported

95 75%

Died

1 0.8%

Euthanised

1 0.8%

Not known

27 21%

Problems reported at the same time

Injection site reaction

96 76%

49 39%

10 7.9%

7 5.6%

7 5.6%

6 4.8%

6 4.8%

5 4.0%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause abnormal cytology in dogs?: 126 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 28 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal cytology with similar medicines

Abnormal cytology after Polysulfated Glycosaminoglycan 21 reports · 0.4% of its reports
Abnormal cytology after Diphenhydramine 52 reports · 1.1% of its reports
Abnormal cytology after Butorphanol 43 reports · 1.0% of its reports
Abnormal cytology after Cefpodoxime 96 reports · 2.4% of its reports
Abnormal cytology after Tramadol 43 reports · 1.1% of its reports
Abnormal cytology after Florfenicol + Mometasone + Terbinafine 88 reports · 2.5% of its reports
Abnormal cytology after Propofol 20 reports · 0.7% of its reports
Abnormal cytology after Isoflurane 31 reports · 1.1% of its reports
Abnormal cytology after Cephalexin 45 reports · 1.7% of its reports
Abnormal cytology after Famotidine 39 reports · 1.5% of its reports

All reported side effects of Melarsomine in dogs · Medicines most reported with abnormal cytology