Abnormal cytology after Tramadol in dogs

43 reports to the FDA describe abnormal cytology in dogs given Tramadol. That is 1.1% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

43Reports
77%Marked serious
9.3%Recovered
33%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
5 15%
1–2 days
4 12%
3–7 days
8 24%
1–4 weeks
4 12%
Over a month
12 36%

How the animals did

Recovered
3 7.0%
Recovered with lasting effects
1 2.3%
Still unwell when reported
21 49%
Died
3 7.0%
Euthanised
11 26%
Not known
4 9.3%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
5
4–7 years
10
8–11 years
23
12+ years
4

About this medicine

Type: medicine.

Questions owners ask

Can Tramadol cause abnormal cytology in dogs?
43 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal cytology with similar medicines

All reported side effects of Tramadol in dogs · Medicines most reported with abnormal cytology