Underdose after Melarsomine (Immiticide) in dogs

The FDA has received 218 reports of underdose in dogs after Melarsomine. That is 1.0% of all reports for this medicine, compared with 1.0% across reports for all dog medicines.

218Reports
74%Marked serious
19%Recovered
2.3%Died or euthanised
62 daysTypical onset
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How soon it started

Same day
25 20%
1–2 days
5 4.0%
3–7 days
4 3.2%
1–4 weeks
19 15%
Over a month
71 57%

How the animals did

Recovered
12 5.5%
Recovered with lasting effects
30 14%
Still unwell when reported
59 27%
Died
2 0.9%
Euthanised
3 1.4%
Not known
112 51%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
103
4–7 years
88
8–11 years
21
12+ years
4

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause underdose in dogs?
218 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 62 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Underdose with similar medicines

All reported side effects of Melarsomine in dogs · Medicines most reported with underdose