Cardiac disorder after Melarsomine (Immiticide) in dogs

588 reports to the FDA describe cardiac disorder in dogs given Melarsomine. That is 2.6% of all reports for this medicine, compared with 1.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

588Reports
98%Marked serious
27%Recovered
4.8%Died or euthanised
187 daysTypical onset
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How soon it started

Same day
13 5.1%
1–2 days
6 2.4%
3–7 days
7 2.8%
1–4 weeks
10 4.0%
Over a month
217 86%

How the animals did

Recovered
12 2.0%
Recovered with lasting effects
145 25%
Still unwell when reported
23 3.9%
Died
21 3.6%
Euthanised
7 1.2%
Not known
380 65%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
278
4–7 years
200
8–11 years
71
12+ years
8

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause cardiac disorder in dogs?
588 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 187 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Cardiac disorder with similar medicines

All reported side effects of Melarsomine in dogs · Medicines most reported with cardiac disorder