Head bobbing after Lufenuron + Milbemycin Oxime (Sentinel) in dogs

28 reports to the FDA describe head bobbing in dogs given Lufenuron + Milbemycin Oxime. That is 0.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines.

28Reports

54%Marked serious

36%Recovered

11%Died or euthanised

Same dayTypical onset

How soon it started

Same day

7 54%

1–2 days

1 7.7%

3–7 days

1 7.7%

1–4 weeks

0 0.0%

Over a month

4 31%

How the animals did

Recovered

10 36%

Still unwell when reported

5 18%

Died

3 11%

Not known

10 36%

Problems reported at the same time

11 39%

9 32%

6 21%

5 18%

5 18%

5 18%

Restlessness or agitation

4 14%

Itching

4 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lufenuron stops flea eggs from developing. Milbemycin Oxime prevents heartworm and controls some intestinal worms (monthly).

Products with this combination include Sentinel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lufenuron + Milbemycin Oxime cause head bobbing in dogs?: 28 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Head bobbing with similar medicines

Head bobbing after Spinosad (Comfortis) 52 reports · 0.1% of its reports

All reported side effects of Lufenuron + Milbemycin Oxime in dogs · Medicines most reported with head bobbing