Underdose after Leptospirosis Vaccine in dogs

The FDA has received 41 reports of underdose in dogs after Leptospirosis Vaccine. That is 0.5% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported less often than average with this medicine.

41Reports

61%Marked serious

27%Recovered

12%Died or euthanised

1 daysTypical onset

How soon it started

Same day

12 34%

1–2 days

7 20%

3–7 days

2 5.7%

1–4 weeks

6 17%

Over a month

8 23%

How the animals did

Recovered

11 27%

Still unwell when reported

17 41%

Died

3 7.3%

Euthanised

2 4.9%

Not known

8 20%

Problems reported at the same time

Vomiting

18 44%

Didn't work as expected

12 29%

12 29%

10 24%

9 22%

9 22%

7 17%

7 17%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause underdose in dogs?: 41 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Underdose with similar medicines

Underdose after Rabies Vaccine 51 reports · 0.5% of its reports
Underdose after Bordetella Vaccine 54 reports · 0.6% of its reports
Underdose after Lyme Vaccine 46 reports · 0.7% of its reports
Underdose after Distemper-parvo Vaccine 47 reports · 0.7% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with underdose