Swollen muzzle after Leptospirosis Vaccine in dogs

The FDA has received 32 reports of swollen muzzle in dogs after Leptospirosis Vaccine. That is 0.4% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

32Reports

88%Marked serious

47%Recovered

0.0%Died or euthanised

Same dayTypical onset

How soon it started

Same day

23 77%

1–2 days

1 3.3%

3–7 days

0 0.0%

1–4 weeks

5 17%

Over a month

1 3.3%

How the animals did

Recovered

15 47%

Still unwell when reported

16 50%

Not known

1 3.1%

Problems reported at the same time

20 63%

15 47%

13 41%

10 31%

7 22%

4 13%

Reddening of the skin

4 13%

Loss of appetite

4 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause swollen muzzle in dogs?: 32 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swollen muzzle with similar medicines

Swollen muzzle after Rabies Vaccine 41 reports · 0.4% of its reports
Swollen muzzle after Bordetella Vaccine 37 reports · 0.4% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with swollen muzzle