Neurological signs after Leptospirosis Vaccine in dogs

The FDA has received 37 reports of neurological signs in dogs after Leptospirosis Vaccine. That is 0.5% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

37Reports

92%Marked serious

11%Recovered

49%Died or euthanised

1 daysTypical onset

How soon it started

Same day

9 33%

1–2 days

6 22%

3–7 days

4 15%

1–4 weeks

6 22%

Over a month

2 7.4%

How the animals did

Recovered

4 11%

Still unwell when reported

12 32%

Died

9 24%

Euthanised

9 24%

Not known

3 8.1%

Problems reported at the same time

18 49%

14 38%

13 35%

13 35%

12 32%

10 27%

9 24%

8 22%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause neurological signs in dogs?: 37 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neurological signs with similar medicines

Neurological signs after Rabies Vaccine 56 reports · 0.6% of its reports
Neurological signs after Bordetella Vaccine 46 reports · 0.5% of its reports
Neurological signs after Distemper-parvo Vaccine 48 reports · 0.7% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with neurological signs