Bradycardia after Leptospirosis Vaccine in dogs

The FDA has received 74 reports of bradycardia in dogs after Leptospirosis Vaccine. That is 0.9% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

74Reports

86%Marked serious

49%Recovered

20%Died or euthanised

Same dayTypical onset

How soon it started

Same day

47 72%

1–2 days

4 6.2%

3–7 days

6 9.2%

1–4 weeks

3 4.6%

Over a month

5 7.7%

How the animals did

Recovered

36 49%

Still unwell when reported

20 27%

Died

6 8.1%

Euthanised

9 12%

Not known

3 4.1%

Problems reported at the same time

45 61%

38 51%

31 42%

29 39%

17 23%

16 22%

15 20%

14 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause bradycardia in dogs?: 74 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Bradycardia with similar medicines

Bradycardia after Rabies Vaccine 94 reports · 0.9% of its reports
Bradycardia after Bordetella Vaccine 91 reports · 1.0% of its reports
Bradycardia after Distemper-parvo Vaccine 52 reports · 0.8% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with bradycardia