Restlessness or agitation after Ketoconazole in dogs

52 reports to the FDA describe restlessness or agitation in dogs given Ketoconazole. That is 2.3% of all reports for this medicine, compared with 1.6% across reports for all dog medicines.

52Reports

62%Marked serious

38%Recovered

7.7%Died or euthanised

3 daysTypical onset

How soon it started

Same day

13 33%

1–2 days

6 15%

3–7 days

5 13%

1–4 weeks

4 10%

Over a month

11 28%

How the animals did

Recovered

17 33%

Recovered with lasting effects

3 5.8%

Still unwell when reported

10 19%

Died

2 3.8%

Euthanised

2 3.8%

Not known

18 35%

Problems reported at the same time

15 29%

13 25%

13 25%

8 15%

8 15%

8 15%

7 13%

7 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Ketoconazole cause restlessness or agitation in dogs?: 52 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Restlessness or agitation with similar medicines

Restlessness or agitation after Melarsomine (Immiticide) 679 reports · 3.0% of its reports
Restlessness or agitation after Polysulfated Glycosaminoglycan 126 reports · 2.3% of its reports
Restlessness or agitation after Diphenhydramine 167 reports · 3.5% of its reports
Restlessness or agitation after Butorphanol 130 reports · 2.9% of its reports
Restlessness or agitation after Cefpodoxime 111 reports · 2.7% of its reports
Restlessness or agitation after Tramadol 131 reports · 3.5% of its reports
Restlessness or agitation after Florfenicol + Mometasone + Terbinafine 80 reports · 2.3% of its reports
Restlessness or agitation after Desoxycorticosterone Pivalate 82 reports · 2.5% of its reports
Restlessness or agitation after Propofol 60 reports · 2.0% of its reports
Restlessness or agitation after Dirlotapide 37 reports · 1.3% of its reports

All reported side effects of Ketoconazole in dogs · Medicines most reported with restlessness or agitation