Breathing problems after Imidacloprid + Moxidectin (Advantage Multi) in dogs
The FDA has received 499 reports of breathing problems in dogs after Imidacloprid + Moxidectin. That is 3.8% of all reports for this medicine, compared with 2.7% across reports for all dog medicines.
499Reports
75%Marked serious
42%Recovered
12%Died or euthanised
Same dayTypical onset
Sponsored
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Imidacloprid kills fleas (spot-on or collar). Moxidectin prevents heartworm disease (monthly topical, or a 6- or 12-month injection for dogs).
Products with this combination include Advantage Multi. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Imidacloprid + Moxidectin cause breathing problems in dogs?
- 499 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within the same day of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Breathing problems with similar medicines
- Breathing problems after Spinosad (Comfortis) 748 reports · 1.3% of its reports
- Breathing problems after Lufenuron + Milbemycin Oxime (Sentinel) 393 reports · 1.5% of its reports
- Breathing problems after Nitenpyram (Capstar) 472 reports · 4.4% of its reports
- Breathing problems after Lufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum) 137 reports · 1.4% of its reports
- Breathing problems after Fipronil + S-methoprene (Frontline Plus) 132 reports · 4.5% of its reports
- Breathing problems after Flumethrin + Imidacloprid (Seresto) 73 reports · 3.2% of its reports
- Breathing problems after Imidacloprid 54 reports · 2.8% of its reports
- Breathing problems after Fipronil 64 reports · 4.5% of its reports
- Breathing problems after Imidacloprid + Permethrin + Pyriproxyfen 34 reports · 4.6% of its reports
- Breathing problems after Cyphenothrin + Fipronil + S-methoprene 51 reports · 7.9% of its reports
All reported side effects of Imidacloprid + Moxidectin in dogs · Medicines most reported with breathing problems