Vocalising after Grapiprant (Galliprant) in dogs

The FDA has received 169 reports of vocalising in dogs after Grapiprant. That is 1.9% of all reports for this medicine, compared with 1.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

169Reports
56%Marked serious
19%Recovered
26%Died or euthanised
13 daysTypical onset
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How soon it started

Same day
31 22%
1–2 days
14 10%
3–7 days
14 10%
1–4 weeks
35 25%
Over a month
45 32%

How the animals did

Recovered
32 19%
Still unwell when reported
65 38%
Died
13 7.7%
Euthanised
31 18%
Not known
28 17%

Problems reported at the same time

Age of the animals

Under 1 year
8
1–3 years
2
4–7 years
12
8–11 years
57
12+ years
87

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause vocalising in dogs?
169 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 13 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vocalising with similar medicines

All reported side effects of Grapiprant in dogs · Medicines most reported with vocalising