Unable to stand after Grapiprant (Galliprant) in dogs

123 reports to the FDA describe unable to stand in dogs given Grapiprant. That is 1.4% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

123Reports
71%Marked serious
14%Recovered
34%Died or euthanised
16 daysTypical onset
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How soon it started

Same day
21 21%
1–2 days
15 15%
3–7 days
5 5.1%
1–4 weeks
16 16%
Over a month
41 42%

How the animals did

Recovered
17 14%
Still unwell when reported
46 37%
Died
10 8.1%
Euthanised
32 26%
Not known
18 15%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
0
4–7 years
9
8–11 years
37
12+ years
72

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause unable to stand in dogs?
123 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 16 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Unable to stand with similar medicines

All reported side effects of Grapiprant in dogs · Medicines most reported with unable to stand