Pale mucous membrane after Grapiprant (Galliprant) in dogs

105 reports to the FDA describe pale mucous membrane in dogs given Grapiprant. That is 1.2% of all reports for this medicine, compared with 0.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

105Reports
93%Marked serious
12%Recovered
43%Died or euthanised
17 daysTypical onset
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How soon it started

Same day
9 13%
1–2 days
4 5.6%
3–7 days
13 18%
1–4 weeks
18 25%
Over a month
27 38%

How the animals did

Recovered
13 12%
Still unwell when reported
36 34%
Died
16 15%
Euthanised
29 28%
Not known
11 10%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
4
4–7 years
11
8–11 years
47
12+ years
42

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause pale mucous membrane in dogs?
105 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 17 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pale mucous membrane with similar medicines

All reported side effects of Grapiprant in dogs · Medicines most reported with pale mucous membrane