Not himself/herself after Grapiprant (Galliprant) in dogs

The FDA has received 69 reports of not himself/herself in dogs after Grapiprant. That is 0.8% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

69Reports
54%Marked serious
8.7%Recovered
17%Died or euthanised
20 daysTypical onset
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How soon it started

Same day
13 22%
1–2 days
10 17%
3–7 days
3 5.2%
1–4 weeks
6 10%
Over a month
26 45%

How the animals did

Recovered
6 8.7%
Still unwell when reported
44 64%
Died
1 1.4%
Euthanised
11 16%
Not known
7 10%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
1
4–7 years
10
8–11 years
17
12+ years
41

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause not himself/herself in dogs?
69 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 20 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Not himself/herself with similar medicines

All reported side effects of Grapiprant in dogs · Medicines most reported with not himself/herself